Journal: Annals of Clinical Microbiology and Antimicrobials
Article Title: Synergistic effect of lactoferrin combined with fluconazole to overcome antifungal resistance in Candida species
doi: 10.1186/s12941-025-00836-1
Figure Lengend Snippet: In vitro activity of the combination of fluconazole (8 µg/mL) and lactoferrin (8 µg/mL) against fluconazole resistant isolates ( a ) C. albicans UPV 15–147 and ( b ) C. albicans UPV 15–157; fluconazole resistant control strains ( c ) C. albicans ATCC 64124 and ( d ) C. parapsilosis NCPF 3153; and fluconazole susceptible control strains ( e ) C. albicans NCPF 3104 and ( f ) C. parapsilosis ATCC 22019
Article Snippet: The efficacy of the combination between fluconazole and lactoferrin was tested by means of time-kill curves against two clinical isolates of fluconazole resistant Candida , in which it was observed synergistic effect ( C. albicans UPV 15–147 and C. albicans UPV 15–157), two fluconazole resistant reference strains ( C. albicans ATCC 64124 and C. parapsilosis NCPF 3104), and two fluconazole susceptible reference strains ( C. albicans NCPF 3153 and C. parapsilosis ATCC 22019).
Techniques: In Vitro, Activity Assay, Control